I have been using this micronised Progesterone cream (Biovea) for a few weeks now. The dose – one full pump is 20mg of Progesterone USP. So far, I can focus better on work, feel more motivated, mood has improved by about 80% and sleep by 100% , and more relaxed since day one. Comparing to HRT (such as Utrogestan) it is of course less effective but its gentler to body and you can regulate your dose and it does not make you that drowsy. (I didnt experiment with higher dose).

The only side effect i noticed was a slight changes in stool.

It does reduce high histamine symptoms and helps a lot in the luteal phase with PMDD or perimenopause symptoms- It’s calming and relaxing, and if you struggle with quality sleep, you probably gonna sleep like a baby.

What is Progesterone USP? ”Progesterone USP (United States Pharmacopeia) is a micronized, “bioidentical” hormone manufactured in a laboratory, primarily derived from plant-based materials. The manufacturing process uses chemical precursors, most commonly diosgenin extracted from wild yams or soybeans, to create a substance chemically identical to the progesterone produced by the human body”.

How to Use Micronised Progesterone Cream

If you are perimenopausal: Use the cream before your expected period, discontinue use for 1-2 days before your period, and start again 10-12 days after your period starts.

If you are menopausal: Apply for 21 consecutive days and discontinue use for 7-10 consecutive days.

Important Timing: It’s generally recommended to use it before sleep as it can make you a bit sedated and drowsy. I personally take it late in the afternoon, but you might figure out your optimal timing yourself based on your schedule. It might not be good if you’re driving unless you use a smaller amount. It is also recommended to start low and increase the dose, letting your body adjust to it. Some people apply a small dose 2x a day—morning and night—while others use it once a day.

WHAT MICRONISED PROGESTERONE CREAM IS USED FOR:

• Other effects: May help with endometriosis, improve overall sense of well-being, generally support weight loss, and protect against osteoporosis.

Biovea also sells:

• Estriol Cream & Progesterone Cream Value Pack
• Dozens more hormone support creams and supplements, including Pregnenolone, Phytoestrogen cream or Melatonin cream

Remember: This is not medical advice. Work with a practitioner familiar with HIT/MCAS/Hormones if possible, especially if you’re on other medications or have complex health issues. Full disclosure.