If you have high histamine issues, and especially POTS (Postural Orthostatic Tachycardia Syndrome), you have greater needs for water intake. Antihistamines can also cause dehydration , and if you experience diarrhea or loose stools, dehydration can worsen quickly. Many people with histamine intolerance agree that taking electrolytes 2–3 times daily significantly decreases their symptoms and helps them recover from acute flare-ups much faster.
Drinking a large glass of water before eating a histamine-loaded meal has been my best substitute for DAO enzyme . However, when drinking more water, it’s also important to increase your electrolyte intake as well. Be mindful, though, that electrolyte imbalances can affect blood pressure and can even lead to dangerous cardiac complications. This is why brands like LMNT are popular among high histamine communities—they offer a lower potassium to higher sodium ratio, no extra additives, no sugar, and no synthetic dyes.
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Check Your Sodium and Potassium Levels
It’s recommended having your sodium and potassium levels tested. Research shows that low levels can lead to worsening of high histamine symptoms (how-to-reduce-mcas-histamine-symptoms) and many people with histamine intolerance fall into the lower range. You need more sodium during summer months. Also If you’re spending time in heat, exercising regularly at the gym, or using a sauna. If your potassium levels are within normal range but sodium is low, you can supplement with sodium chloride tablets (Amazon).

Best Electrolyte Brands for Histamine Intolerance & MCAS
(Amazon)
- LMNT is most popular but contains citric Acid
- Vitassium
- Normalyte
- Relyte unflavoured, contains coconut water powder instead of sugars
- Hoorbach electrolyte tablets
- Liquid IV (not recommended if on strict low Histamine diet)
Freak Athletics (Amazon) I have been personally using this powder without any issue, sugar-free, no additives.
You can also use an alternative—a whole dried goat milk powder (Amazon). Goat milk is packed with minerals and is actually beneficial for allergy symptoms. if you can tolerate it. It’s good to use before a workout with berries. https://pmc.ncbi.nlm.nih.gov/articles/PMC7040033/
How to Choose the Right Electrolytes
- Choose products without citric acid; opt for malic acid instead
- Avoid artificial sweeteners
- Avoid high-fructose corn syrup
- Select low-sugar options



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